Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure
Objective: Melanocortin 2 receptor accessory protein 2 (MRAP2) has a critical role in energy homeostasis.Although MRAP2 has been shown to regulates a number of GPCRs involved in metabolism, the key neurons responsible for the Pentair EasyTouch Parts phenotype of gross obesity in MRAP2 deficient animals are unclear.Furthermore, to date, all the muri